What's new for 'JKB_daily1' in PubMed

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Sender's message: Sepsis or genomics or altitude: JKB_daily1

Sent on Saturday, 2010 Feb 13
Search (sepsis[MeSH Terms] OR septic shock[MeSH Terms] OR altitude[MeSH Terms] OR genomics[MeSH Terms] OR genetics[MeSH Terms] OR retrotransposons[MeSH Terms] OR macrophage[MeSH Terms]) AND ("2009/8/8"[Publication Date] : "3000"[Publication Date]) AND (("Science"[Journal] OR "Nature"[Journal] OR "The New England journal of medicine"[Journal] OR "Lancet"[Journal] OR "Nature genetics"[Journal] OR "Nature medicine"[Journal]) OR (Hume DA[Author] OR Baillie JK[Author] OR Faulkner, Geoffrey J[Author]))
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PubMed Results

Items 1 -4 of 4

1.	Nature. 2010 Jan 7;463(7277):25. Icelandic genetic database not at risk from bankruptcy. Stefánsson K. Comment on: Nature. 2009 Nov 26;462(7272):401.
	PMID: 20054376 [PubMed - indexed for MEDLINE]
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	Publication Types: Comment Letter MeSH Terms: Databases, Genetic/economics* Databases, Genetic/trends* Genetics, Medical Genome, Human Genomics/economics* Genomics/trends* Humans Iceland

2.	Nature. 2010 Jan 7;463(7277):12-3. New year, new science. Van Noorden R.
	PMID: 20054366 [PubMed - indexed for MEDLINE]
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	Publication Types: News MeSH Terms: Animals Astronomy Climate Conservation of Natural Resources Embryonic Stem Cells/transplantation Genomics HIV Infections/prevention & control Humans Lasers Nuclear Reprogramming Physics Science/trends* Space Flight Systems Biology

3.	Nat Genet. 2010 Jan;42(1):13-4. Exome sequencing makes medical genomics a reality. Biesecker LG. Comment on: Nat Genet. 2010 Jan;42(1):30-5. Massively parallel sequencing of the exomes of four individuals with Miller syndrome, combined with filtering to exclude benign and unrelated variants, has identified causative mutations in DHODH. This approach will accelerate discovery of the genetic bases of hundreds of other rare mendelian disorders.
	PMID: 20037612 [PubMed - indexed for MEDLINE]
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	Publication Types: Comment News MeSH Terms: Abnormalities, Multiple/genetics Abnormalities, Multiple/pathology Exons/genetics* Genetic Predisposition to Disease Genetics, Medical/methods* Genomics/methods* Humans Mandibulofacial Dysostosis/pathology Mutation Open Reading Frames/genetics Oxidoreductases Acting on CH-CH Group Donors/genetics Sequence Analysis, DNA/methods* Syndrome Substances: Oxidoreductases Acting on CH-CH Group Donors dihydroorotate dehydrogenase

4.	Nat Genet. 2010 Jan;42(1):62-7. Epub 2009 Dec 6. Geographical genomics of human leukocyte gene expression variation in southern Morocco. Idaghdour Y, Czika W, Shianna KV, Lee SH, Visscher PM, Martin HC, Miclaus K, Jadallah SJ, Goldstein DB, Wolfinger RD, Gibson G. Department of Genetics, North Carolina State University, Raleigh, North Carolina, USA. Studies of the genetics of gene expression can identify expression SNPs (eSNPs) that explain variation in transcript abundance. Here we address the robustness of eSNP associations to environmental geography and population structure in a comparison of 194 Arab and Amazigh individuals from a city and two villages in southern Morocco. Gene expression differed between pairs of locations for up to a third of all transcripts, with notable enrichment of transcripts involved in ribosomal biosynthesis and oxidative phosphorylation. Robust associations were observed in the leukocyte samples: cis eSNPs (P < 10(-08)) were identified for 346 genes, and trans eSNPs (P < 10(-11)) for 10 genes. All of these associations were consistent both across the three sample locations and after controlling for ancestry and relatedness. No evidence of large-effect trans-acting mediators of the pervasive environmental influence was found; instead, genetic and environmental factors acted in a largely additive manner. PMCID: PMC2798927 [Available on 2010/7/1]
	PMID: 19966804 [PubMed - indexed for MEDLINE]
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	Publication Types: Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. MeSH Terms: Arabs/genetics Gene Expression Profiling/methods* Genetic Predisposition to Disease Genetic Variation* Genetics, Population Genome-Wide Association Study Genomics/methods* Geography Humans Leukocytes/metabolism* Morocco Polymorphism, Single Nucleotide Principal Component Analysis Secondary Source ID: GEO/GSE17065