Tuesday, 3 June 2014

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Sender's message: Sepsis or genomics or altitude: JKB_daily1

Sent on Tuesday, 2014 June 03
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PubMed Results
Items 1 - 2 of 2

1. N Engl J Med. 2014 May 15;370(20):1874-7. doi: 10.1056/NEJMp1400613.

The biology and genetics of obesity--a century of inquiries.

Jou C.

Author information:
From the Department of the History of Science, Harvard University, Cambridge, MA.

Free Article
PMID: 24827033 [PubMed - indexed for MEDLINE]
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2. Science. 2014 May 16;344(6185):747-50. doi: 10.1126/science.1253448. Epub 2014 Apr 24.

Genomic diversity and admixture differs for Stone-Age Scandinavian foragers and farmers.

Skoglund P1, Malmström H1, Omrak A2, Raghavan M3, Valdiosera C4, Günther T1, Hall P5, Tambets K6, Parik J6, Sjögren KG7, Apel J8, Willerslev E3, Storå J2, Götherström A9, Jakobsson M10.

Author information:
1Department of Evolutionary Biology, Uppsala University, Uppsala 752 36, Sweden.
2Department of Archaeology and Classical studies, Stockholm University, Stockholm 106 91, Sweden.
3Centre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen, Copenhagen 1350, Denmark.
4Department of Archaeology, Environment and Community Planning, La Trobe University, Melbourne VIC 3086, Australia.
5Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm 171 77, Sweden.
6Evolutionary Biology Group, Estonian Biocentre and University of Tartu, Tartu 51010, Estonia.
7Department of Historical Studies, University of Gothenburg, Gothenburg, 405 30, Sweden.
8Department of Archaeology and Ancient History, Lund University, Lund, 221 00, Sweden.
9Department of Archaeology and Classical studies, Stockholm University, Stockholm 106 91, Sweden. tsarapkin@googlemail.com mattias.jakobsson@ebc.uu.se.
10Department of Evolutionary Biology, Uppsala University, Uppsala 752 36, Sweden. Science for Life Laboratory, Uppsala University, Uppsala 752 36, Sweden. tsarapkin@googlemail.com mattias.jakobsson@ebc.uu.se.

Abstract

Prehistoric population structure associated with the transition to an agricultural lifestyle in Europe remains a contentious idea. Population-genomic data from 11 Scandinavian Stone Age human remains suggest that hunter-gatherers had lower genetic diversity than that of farmers. Despite their close geographical proximity, the genetic differentiation between the two Stone Age groups was greater than that observed among extant European populations. Additionally, the Scandinavian Neolithic farmers exhibited a greater degree of hunter-gatherer-related admixture than that of the Tyrolean Iceman, who also originated from a farming context. In contrast, Scandinavian hunter-gatherers displayed no significant evidence of introgression from farmers. Our findings suggest that Stone Age foraging groups were historically in low numbers, likely owing to oscillating living conditions or restricted carrying capacity, and that they were partially incorporated into expanding farming groups.

Copyright © 2014, American Association for the Advancement of Science.

PMID: 24762536 [PubMed - indexed for MEDLINE]
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