What's new for 'JKB_daily1' in PubMed

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Sender's message: Sepsis or genomics or altitude: JKB_daily1

Sent on Saturday, 2012 May 19
Search: (sepsis[MeSH Terms] OR septic shock[MeSH Terms] OR altitude[MeSH Terms] OR genomics[MeSH Terms] OR genetics[MeSH Terms] OR retrotransposons[MeSH Terms] OR macrophage[MeSH Terms]) AND ("2009/8/8"[Publication Date] : "3000"[Publication Date]) AND (("Science"[Journal] OR "Nature"[Journal] OR "The New England journal of medicine"[Journal] OR "Lancet"[Journal] OR "Nature genetics"[Journal] OR "Nature medicine"[Journal]) OR (Hume DA[Author] OR Baillie JK[Author] OR Faulkner, Geoffrey J[Author]))

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PubMed Results

Items 1 - 5 of 5

1.	Nature. 2012 Apr 5;484(7392):133. Turning point: Jessica Ware. Interviewed by Virginia Gewin. Ware J.
	PMID: 22486001 [PubMed - indexed for MEDLINE]
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2.	Nature. 2012 Apr 4;484(7392):55-61. doi: 10.1038/nature10944. The genomic basis of adaptive evolution in threespine sticklebacks. Jones FC, Grabherr MG, Chan YF, Russell P, Mauceli E, Johnson J, Swofford R, Pirun M, Zody MC, White S, Birney E, Searle S , Schmutz J, Grimwood J, Dickson MC, Myers RM, Miller CT, Summers BR, Knecht AK, Brady SD, Zhang H, Pollen AA, Howes T, Amemiya C; Broad Institute Genome Sequencing Platform & Whole Genome Assembly Team, Baldwin J, Bloom T, Jaffe DB, Nicol R, Wilkinson J, Lander ES, Di Palma F, Lindblad-Toh K, Kingsley DM. Source Department of Developmental Biology, Beckman Center B300, Stanford University School of Medicine, Stanford California 94305, USA. Comment in Nature. 2012 Apr 5;484(7392):46-7. Abstract Marine stickleback fish have colonized and adapted to thousands of streams and lakes formed since the last ice age, providing an exceptional opportunity to characterize genomic mechanisms underlying repeated ecological adaptation in nature. Here we develop a high-quality reference genome assembly for threespine sticklebacks. By sequencing the genomes of twenty additional individuals from a global set of marine and freshwater populations, we identify a genome-wide set of loci that are consistently associated with marine-freshwater divergence. Our results indicate that reuse of globally shared standing genetic variation, including chromosomal inversions, has an important role in repeated evolution of distinct marine and freshwater sticklebacks, and in the maintenance of divergent ecotypes during early stages of reproductive isolation. Both coding and regulatory changes occur in the set of loci underlying marine-freshwater evolution, but regulatory changes appear to predominate in this well known example of repeated adaptive evolution in nature. PMCID: PMC3322419 [Available on 2012/10/5]
	PMID: 22481358 [PubMed - indexed for MEDLINE]
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3.	Nature. 2012 Apr 4;484(7392):21-3. doi: 10.1038/484021a. Infectious disease: Blowing in the wind. Frazer J.
	PMID: 22481336 [PubMed - indexed for MEDLINE]
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4.	Nature. 2012 Apr 2;484(7392):19. doi: 10.1038/484019a. Glaciologists to target third pole. Qiu J.
	PMID: 22481333 [PubMed - indexed for MEDLINE]
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5.	Nature. 2012 Mar 18;484(7392):101-4. doi: 10.1038/nature10905. Endospore abundance, microbial growth and necromass turnover in deep sub-seafloor sediment. Lomstein BA, Langerhuus AT, D'Hondt S, Jørgensen BB, Spivack AJ. Source Department of Bioscience, Section for Microbiology, Aarhus University, Building 1540, Ny Munkegade 114, DK-8000 Aarhus C, Denmark. bente.lomstein@biology.au.dk Abstract Two decades of scientific ocean drilling have demonstrated widespread microbial life in deep sub-seafloor sediment, and surprisingly high microbial-cell numbers. Despite the ubiquity of life in the deep biosphere, the large community sizes and the low energy fluxes in this vast buried ecosystem are not yet understood. It is not known whether organisms of the deep biosphere are specifically adapted to extremely low energy fluxes or whether most of the observed cells are in a dormant, spore-like state. Here we apply a new approach--the D:L-amino-acid model--to quantify the distributions and turnover times of living microbial biomass, endospores and microbial necromass, as well as to determine their role in the sub-seafloor carbon budget. The approach combines sensitive analyses of unique bacterial markers (muramic acid and D-amino acids) and the bacterial endospore marker, dipicolinic acid, with racemization dynamics of stereo-isomeric amino acids. Endospores are as abundant as vegetative cells and microbial activity is extremely low, leading to microbial biomass turnover times of hundreds to thousands of years. We infer from model calculations that biomass production is sustained by organic carbon deposited from the surface photosynthetic world millions of years ago and that microbial necromass is recycled over timescales of hundreds of thousands of years.
	PMID: 22425999 [PubMed - indexed for MEDLINE]
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