Tuesday, 18 September 2012

What's new for 'JKB_daily1' in PubMed

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Sender's message: Sepsis or genomics or altitude: JKB_daily1

Sent on Tuesday, 2012 September 18
Search: (sepsis[MeSH Terms] OR septic shock[MeSH Terms] OR altitude[MeSH Terms] OR genomics[MeSH Terms] OR genetics[MeSH Terms] OR retrotransposons[MeSH Terms] OR macrophage[MeSH Terms]) AND ("2009/8/8"[Publication Date] : "3000"[Publication Date]) AND (("Science"[Journal] OR "Nature"[Journal] OR "The New England journal of medicine"[Journal] OR "Lancet"[Journal] OR "Nature genetics"[Journal] OR "Nature medicine"[Journal]) OR (Hume DA[Author] OR Baillie JK[Author] OR Faulkner, Geoffrey J[Author]))

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PubMed Results
Items 1 - 4 of 4

1. Science. 2012 Sep 7;337(6099):1167-9.

Profile: Ewan Birney. Genomics' big talker.

Pennisi E.
PMID: 22955814 [PubMed - indexed for MEDLINE]
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2. Science. 2012 Sep 7;337(6099):1159, 1161.

Genomics. ENCODE project writes eulogy for junk DNA.

Pennisi E.
PMID: 22955811 [PubMed - indexed for MEDLINE]
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3. Science. 2012 Aug 31;337(6098):1107-11.

The shared antibiotic resistome of soil bacteria and human pathogens.

Forsberg KJ, Reyes A, Wang B, Selleck EM, Sommer MO, Dantas G.

Source

Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St. Louis, MO 63108, USA.

Abstract

Soil microbiota represent one of the ancient evolutionary origins of antibiotic resistance and have been proposed as a reservoir of resistance genes available for exchange with clinical pathogens. Using a high-throughput functional metagenomic approach in conjunction with a pipeline for the de novo assembly of short-read sequence data from functional selections (termed PARFuMS), we provide evidence for recent exchange of antibiotic resistance genes between environmental bacteria and clinical pathogens. We describe multidrug-resistant soil bacteria containing resistance cassettes against five classes of antibiotics (β-lactams, aminoglycosides, amphenicols, sulfonamides, and tetracyclines) that have perfect nucleotide identity to genes from diverse human pathogens. This identity encompasses noncoding regions as well as multiple mobilization sequences, offering not only evidence of lateral exchange but also a mechanism by which antibiotic resistance disseminates.

PMID: 22936781 [PubMed - indexed for MEDLINE]
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4. Science. 2012 Aug 31;337(6098):1036.

Immunology. Stalling sepsis?

Leslie M.
PMID: 22936753 [PubMed - indexed for MEDLINE]
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