What's new for 'JKB_daily1' in PubMed

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Sender's message: Sepsis or genomics or altitude: JKB_daily1

Sent on Thursday, 2011 Mar 03
Search (sepsis[MeSH Terms] OR septic shock[MeSH Terms] OR altitude[MeSH Terms] OR genomics[MeSH Terms] OR genetics[MeSH Terms] OR retrotransposons[MeSH Terms] OR macrophage[MeSH Terms]) AND ("2009/8/8"[Publication Date] : "3000"[Publication Date]) AND (("Science"[Journal] OR "Nature"[Journal] OR "The New England journal of medicine"[Journal] OR "Lancet"[Journal] OR "Nature genetics"[Journal] OR "Nature medicine"[Journal]) OR (Hume DA[Author] OR Baillie JK[Author] OR Faulkner, Geoffrey J[Author]))
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PubMed Results

Items 1 - 15 of 15

1.	Nature. 2011 Feb 17;470(7334):338-9. Genomics: Drugs, diabetes and cancer. Birnbaum MJ, Shaw RJ.
	PMID: 21331030 [PubMed - indexed for MEDLINE]
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2.	Nature. 2011 Feb 17;470(7334):327-9. Health-care hit or miss? Hersh W, Jacko JA, Greenes R, Tan J, Janies D, Embi PJ, Payne PR.
	PMID: 21331020 [PubMed - indexed for MEDLINE]
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3.	Nature. 2011 Feb 17;470(7334):305-6. Devil in the details. [No authors listed]
	PMID: 21 330998 [PubMed - indexed for MEDLINE]
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4.	Science. 2011 Feb 11;331(6018):775-8. Leishmania RNA virus controls the severity of mucocutaneous leishmaniasis. Ives A, Ronet C, Prevel F, Ruzzante G, Fuertes-Marraco S, Schutz F, Zangger H, Revaz-Breton M, Lye LF, Hickerson SM, Beverley SM, Acha-Orbea H, Launois P, Fasel N, Masina S. Department of Biochemistry, University of Lausanne, 1066 Epalinges, Switzerland. Abstract Mucocutaneous leishmaniasis is caused by infections with intracellular parasites of the Leishmania Viannia subgenus, including Leishmania guyanensis. The pathology develops after parasite dissemination to nasopharyngeal tissues, where destructive metastatic lesions form with chronic inflammation. Currently, the mechanisms involved in lesion development are poorly understood. Here we show that metastasizing parasites have a high Leishmania RNA virus-1 (LRV1) burden that is recognized by the host Toll-like receptor 3 (TLR3) to induce proinflammatory cytokines and chemokines. Paradoxically, these TLR3-mediated immune responses rendered mice more susceptible to infection, and the animals developed an increased footpad swelling and parasitemia. Thus, LRV1 in the metastasizing parasites subverted the host immune response to Leishmania and promoted parasite persistence.
	PMID: 21311023 [PubMed - indexed for MEDLINE]
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5.	Science. 2011 Feb 11;331(6018):728-9. On the future of genomic data. Kahn SD. Illumina, 9885 Towne Centre Drive, San Diego, CA 92121, USA. Abstract Many of the challenges in genomics derive from the informatics needed to store and analyze the raw sequencing data that is available from highly multiplexed sequencing technologies. Because single week-long sequencing runs today can produce as much data as did entire genome centers a few years ago, the need to process terabytes of information has become de rigueur for many labs engaged in genomic research. The availability of deep (and large) genomic data sets raises concerns over information access, data security, and subject/patient privacy that must be addressed for the field to continue its rapid advances.
	PMID: 21311016 [PubMed - indexed for MEDLINE]
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6.	Science. 2011 Feb 11;331(6018):691. Genome-sequencing anniversary. What will drive genomics over the next 10 year s? Caplan A. Center for Bioethics, University of Pennsylvania, Philadelphia, PA, USA.
	PMID: 21311001 [PubMed - indexed for MEDLINE]
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7.	Science. 2011 Feb 11;331(6018):691. Genome-sequencing anniversary. An anniversary party. Stefánsson K. deCode Genetics, Reykjavik, Iceland.
	PMID: 21311000 [PubMed - indexed for MEDLINE]
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8.	Science. 2011 Feb 11;331(6018):691. Genome-sequencing anniversary. First steps on a long road. Schadt E. Pacific Biosciences of California, Menlo Park, CA, USA.
	PMID: 21310999 [PubMed - indexed for MEDLINE]
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9.	Science. 2011 Feb 11;331(6018):690. Genome-sequencing anniversary. Personal genomes: for one and for all. Wang J. Beijing Genome Institute.
	PMID: 21310998 [PubMed - indexed for MEDLINE]
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10.	Science. 2011 Feb 11;331(6018):690-1. Genome-sequencing anniversary. My genome, my identity, my health. Royal CD. Institute for Genome Sciences & Policy and Department of African and African American Studies, Duke University, Durham, NC, USA.
	PMID: 21310996 [PubMed - indexed for MEDLINE]
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11.	Science. 2011 Feb 11;331(6018):689. Genome-sequencing anniversary. My genome. Tutu D.
	PMID: 21310994 [PubMed - indexed for MEDLINE]
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12.	Science. 2011 Feb 11;331(6018):689-90. Genome-sequencing anniversary. Genome literacy. Dermitzakis ET. Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland.
	PMID: 21310993 [PubMed - indexed for MEDLINE]
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13.	Science. 2011 Feb 11;331(6018):666-8. Human genome 10th anniversary. Will computers crash genomics? Pennisi E.
	PMID: 21310981 [PubMed - indexed for MEDLINE]
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14.	Science. 2011 Feb 11;331(6018):662-5. Human genome 10th anniversary. What would you do? Couzin-Frankel J.
	PMID: 21310980 [PubMed - indexed for MEDLINE]
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15.	Science. 2011 Feb 11;331(6018):660. Biomedical research. The genome project: what will it do as a teenager? Inte rview by Jocelyn Kaiser. Green E.
	PMID: 21310978 [PubMed - indexed for MEDLINE]
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