Thursday, 20 September 2012

What's new for 'JKB_daily1' in PubMed

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Sender's message: Sepsis or genomics or altitude: JKB_daily1

Sent on Thursday, 2012 September 20
Search: (sepsis[MeSH Terms] OR septic shock[MeSH Terms] OR altitude[MeSH Terms] OR genomics[MeSH Terms] OR genetics[MeSH Terms] OR retrotransposons[MeSH Terms] OR macrophage[MeSH Terms]) AND ("2009/8/8"[Publication Date] : "3000"[Publication Date]) AND (("Science"[Journal] OR "Nature"[Journal] OR "The New England journal of medicine"[Journal] OR "Lancet"[Journal] OR "Nature genetics"[Journal] OR "Nature medicine"[Journal]) OR (Hume DA[Author] OR Baillie JK[Author] OR Faulkner, Geoffrey J[Author]))

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PubMed Results
Items 1 - 8 of 8

1. Nat Med. 2012 Jul 6;18(7):1041-51. doi: 10.1038/nm.2829.

From prenatal genomic diagnosis to fetal personalized medicine: progress and challenges.

Bianchi DW.

Source

The Mother Infant Research Institute at Tufts Medical Center and the Division of Genetics, Department of Pediatrics, Floating Hospital for Children, Boston, Massachusetts, USA. dbianchi@tuftsmedicalcenter.org

Abstract

Thus far, the focus of personalized medicine has been the prevention and treatment of conditions that affect adults. Although advances in genetic technology have been applied more frequently to prenatal diagnosis than to fetal treatment, genetic and genomic information is beginning to influence pregnancy management. Recent developments in sequencing the fetal genome combined with progress in understanding fetal physiology using gene expression arrays indicate that we could have the technical capabilities to apply an individualized medicine approach to the fetus. Here I review recent advances in prenatal genetic diagnostics, the challenges associated with these new technologies and how the information derived from them can be used to advance fetal care. Historically, the goal of prenatal diagnosis has been to provide an informed choice to prospective parents. We are now at a point where that goal can and should be expanded to incorporate genetic, genomic and transcriptomic data to develop new approaches to fetal treatment.

PMID: 22772565 [PubMed - indexed for MEDLINE]
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2. Nat Med. 2012 Jul 6;18(7):1002. doi: 10.1038/nm0712-1002.

Straight talk with...Phillip Dellinger. Interviewed by Roxanne Khamsi.

Dellinger P.
PMID: 22772544 [PubMed - indexed for MEDLINE]
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3. Nat Med. 2012 Jul 6;18(7):1001. doi: 10.1038/nm0712-1001.

After Xigris, researchers look to new targets to combat sepsis.

Williams SC.
PMID: 22772543 [PubMed - indexed for MEDLINE]
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4. Nat Med. 2012 Jul 6;18(7):1000. doi: 10.1038/nm0712-1000.

Trial failure prompts soul-searching for critical-care specialists.

Dolgin E.
PMID: 22772542 [PubMed - indexed for MEDLINE]
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5. Nat Med. 2012 Jul 6;18(7):999. doi: 10.1038/nm0712-999.

New biomarkers sought for improving sepsis management and care.

Moyer MW.
PMID: 22772541 [PubMed - indexed for MEDLINE]
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6. Nat Med. 2012 Jul 6;18(7):998-9. doi: 10.1038/nm0712-998b.

Execution of sepsis trials needs an overhaul, experts say.

Khamsi R.
PMID: 22772540 [PubMed - indexed for MEDLINE]
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7. Nat Med. 2012 Jul 6;18(7):998. doi: 10.1038/nm0712-998a.

Rodent models of sepsis found shockingly lacking.

Raven K.
PMID: 22772539 [PubMed - indexed for MEDLINE]
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8. Nat Med. 2012 Jul 6;18(7):997. doi: 10.1038/nm0712-997.

Focus on sepsis.

[No authors listed]
PMID: 22772538 [PubMed - indexed for MEDLINE]
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