Thursday, 25 October 2012

What's new for 'JKB_daily1' in PubMed

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Sender's message: Sepsis or genomics or altitude: JKB_daily1

Sent on Thursday, 2012 October 25
Search: (sepsis[MeSH Terms] OR septic shock[MeSH Terms] OR altitude[MeSH Terms] OR genomics[MeSH Terms] OR genetics[MeSH Terms] OR retrotransposons[MeSH Terms] OR macrophage[MeSH Terms]) AND ("2009/8/8"[Publication Date] : "3000"[Publication Date]) AND (("Science"[Journal] OR "Nature"[Journal] OR "The New England journal of medicine"[Journal] OR "Lancet"[Journal] OR "Nature genetics"[Journal] OR "Nature medicine"[Journal]) OR (Hume DA[Author] OR Baillie JK[Author] OR Faulkner, Geoffrey J[Author]))

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PubMed Results
Items 1 - 3 of 3

1. Science. 2012 Oct 19;338(6105):321-3. doi: 10.1126/science.338.6105.321.

Cell biology. Looking for a sugar rush.

Service RF.
PMID: 23087226 [PubMed - indexed for MEDLINE]
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2. Lancet. 2012 Oct 13;380(9850):1358. doi: 10.1016/S0140-6736(12)60911-8.

NDM-1 polymicrobial infections including Vibrio cholerae.

Darley E, Weeks J, Jones L, Daniels V, Wootton M, MacGowan A, Walsh T.

Source

Medical Microbiology, North Bristol NHS Trust, Bristol, UK.

PMID: 23063285 [PubMed - indexed for MEDLINE]
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3. Science. 2012 Oct 19;338(6105):374-9. doi: 10.1126/science.1227721. Epub 2012 Sep 20.

Genomic variation in seven Khoe-San groups reveals adaptation and complex African history.

Schlebusch CM, Skoglund P, Sjödin P, Gattepaille LM, Hernandez D, Jay F, Li S, De Jongh M, Singleton A, Blum MG, Soodyall H, Jakobsson M.

Source

Department of Evolutionary Biology, Uppsala University, Norbyvägen 18D, 752 36 Uppsala, Sweden. carina.schlebusch@ebc.uu.se

Abstract

The history of click-speaking Khoe-San, and African populations in general, remains poorly understood. We genotyped ~2.3 million single-nucleotide polymorphisms in 220 southern Africans and found that the Khoe-San diverged from other populations ≥100,000 years ago, but population structure within the Khoe-San dated back to about 35,000 years ago. Genetic variation in various sub-Saharan populations did not localize the origin of modern humans to a single geographic region within Africa; instead, it indicated a history of admixture and stratification. We found evidence of adaptation targeting muscle function and immune response; potential adaptive introgression of protection from ultraviolet light; and selection predating modern human diversification, involving skeletal and neurological development. These new findings illustrate the importance of African genomic diversity in understanding human evolutionary history.

PMID: 22997136 [PubMed - indexed for MEDLINE]
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