What's new for 'JKB_daily1' in PubMed

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Sender's message: Sepsis or genomics or altitude: JKB_daily1

Sent on Wednesday, 2012 November 14
Search: (sepsis[MeSH Terms] OR septic shock[MeSH Terms] OR altitude[MeSH Terms] OR genomics[MeSH Terms] OR genetics[MeSH Terms] OR retrotransposons[MeSH Terms] OR macrophage[MeSH Terms]) AND ("2009/8/8"[Publication Date] : "3000"[Publication Date]) AND (("Science"[Journal] OR "Nature"[Journal] OR "The New England journal of medicine"[Journal] OR "Lancet"[Journal] OR "Nature genetics"[Journal] OR "Nature medicine"[Journal]) OR (Hume DA[Author] OR Baillie JK[Author] OR Faulkner, Geoffrey J[Author]))

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PubMed Results

Items 1 - 3 of 3

1.	Nat Med. 2012 Sep;18(9):1346-7. doi: 10.1038/nm.2930. The not-so-simple HDL story: A new era for quantifying HDL and cardiovascular risk? Heinecke JW. Department of Medicine, University of Washington, Seattle, Washington, USA. heinecke@u.washington.edu
	PMID: 22961165 [PubMed - indexed for MEDLINE]
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2.	Nat Med. 2012 Sep;18(9):1344-6. doi: 10.1038/nm.2937. The not-so-simple HDL story: Is it time to revise the HDL cholesterol hypothesis? Rader DJ, Tall AR. Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA. rader@mail.med.upenn.edu
	PMID: 22961164 [PubMed - indexed for MEDLINE]
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3.	Nat Med. 2012 Sep;18(9):1434-40. On silico peptide microarrays for high-resolution mapping of antibody epitopes and diverse protein-protein interactions. Price JV, Tangsombatvisit S, Xu G, Yu J, Levy D, Baechler EC, Gozani O, Varma M, Utz PJ, Liu CL. Department of Medicine, Division of Immunology and Rheumatology, Stanford School of Medicine, Stanford, California, USA. Abstract We developed a new, silicon-based peptide array for a broad range of biological applications, including potential development as a real-time point-of-care platform. We used photolithography on silicon wafers to synthesize microarrays (Intel arrays) that contained every possible overlapping peptide within a linear protein sequence covering the N-terminal tail of human histone H2B. These arrays also included peptides with acetylated and methylated lysine residues, reflecting post-translational modifications of H2B. We defined minimum binding epitopes for commercial antibodies recognizing the modified and unmodified H2B peptides. We further found that this platform is suitable for the highly sensitive characterization of methyltransferases and kinase substrates. The Intel arrays also revealed specific H2B epitopes that are recognized by autoantibodies in individuals with systemic lupus erythematosus who have elevated disease severity. By combining emerging nonfluorescence-based detection methods with an underlying integrated circuit, we are now poised to create a truly transformative proteomics platform with applications in bioscience, drug development and clinical diagnostics. PMCID: PMC3491111 [Available on 2013/3/1]
	PMID: 22902875 [PubMed - indexed for MEDLINE]
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