Thursday, 10 July 2014

What's new for 'JKB_daily1' in PubMed

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Sender's message: Sepsis or genomics or altitude: JKB_daily1

Sent on Thursday, 2014 July 10
Search: (sepsis[MeSH Terms] OR septic shock[MeSH Terms] OR altitude[MeSH Terms] OR genomics[MeSH Terms] OR genetics[MeSH Terms] OR retrotransposons[MeSH Terms] OR macrophage[MeSH Terms]) AND ("2009/8/8"[Publication Date] : "3000"[Publication Date]) AND (("Science"[Journal] OR "Nature"[Journal] OR "The New England journal of medicine"[Journal] OR "Lancet"[Journal] OR "Nature genetics"[Journal] OR "Nature medicine"[Journal]) OR (Hume DA[Author] OR Baillie JK[Author] OR Faulkner, Geoffrey J[Author]))

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PubMed Results
Items 1 - 3 of 3

1. Science. 2014 Jun 20;344(6190):1410-4. doi: 10.1126/science.1253226.

The genomic landscape underlying phenotypic integrity in the face of gene flow in crows.

Poelstra JW1, Vijay N1, Bossu CM1, Lantz H2, Ryll B3, Müller I4, Baglione V5, Unneberg P6, Wikelski M4, Grabherr MG7, Wolf JB8.

Author information:
1Science for Life Laboratory and Department of Evolutionary Biology, Evolutionary Biology Centre, Uppsala University, 75236 Uppsala, Sweden.
2Bioinformatics Infrastructure for Life Sciences, Uppsala University, 75124 Uppsala, Sweden. Science for Life Laboratory and Department of Medical Biochemistry and Microbiology, Uppsala University, 75123 Uppsala, Sweden.
3Department of Organismal Biology, Evolutionary Biology Centre, Uppsala University, 75236 Uppsala, Sweden.
4Max Planck Institute for Ornithology, 78315 Radolfzell, Germany. Department of Biology, University of Konstanz, 78464 Konstanz, Germany.
5Departamento de Ciencias Agro-Forestales, Campus La Yutera, Universidad de Valladolid, 34004 Palencia, Spain.
6Science for Life Laboratory and Department of Biochemistry and Biophysics, Stockholm University, 171 21 Solna, Sweden.
7Science for Life Laboratory and Department of Medical Biochemistry and Microbiology, Uppsala University, 75123 Uppsala, Sweden.
8Science for Life Laboratory and Department of Evolutionary Biology, Evolutionary Biology Centre, Uppsala University, 75236 Uppsala, Sweden. jochen.wolf@ebc.uu.se.

Comment in

Abstract

The importance, extent, and mode of interspecific gene flow for the evolution of species has long been debated. Characterization of genomic differentiation in a classic example of hybridization between all-black carrion crows and gray-coated hooded crows identified genome-wide introgression extending far beyond the morphological hybrid zone. Gene expression divergence was concentrated in pigmentation genes expressed in gray versus black feather follicles. Only a small number of narrow genomic islands exhibited resistance to gene flow. One prominent genomic region (<2 megabases) harbored 81 of all 82 fixed differences (of 8.4 million single-nucleotide polymorphisms in total) linking genes involved in pigmentation and in visual perception-a genomic signal reflecting color-mediated prezygotic isolation. Thus, localized genomic selection can cause marked heterogeneity in introgression landscapes while maintaining phenotypic divergence.

Copyright © 2014, American Association for the Advancement of Science.

PMID: 24948738 [PubMed - indexed for MEDLINE]
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2. Science. 2014 Jun 20;344(6190):1346-8. doi: 10.1126/science.1251546.

Research capacity. Enabling the genomic revolution in Africa.

H3Africa Consortium.

Collaborators: Matovu E, Bucheton B, Chisi J, Enyaru J, Hertz-Fowler C, Koffi M, Macleod A, Mumba D, Sidibe I, Simo G, Simuunza M, Mayosi B, Ramesar R, Mulder N, Ogendo S, Mocumbi AO, Hugo-Hamman C, Ogah O, El Sayed A, Mondo C, Musuku J, Engel M, De Vries J, Lesosky M, Shaboodien G, Cordell H, Paré G, Keavney B, Motala A, Sobngwi E, Mbanya JC, Hennig B, Balde N, Nyirenda M, Oli J, Adebamowo C, Levitt N, Mayige M, Kapiga S, Kaleebu P, Sandhu M, Smeeth L, McCarthy M, Rotimi C.

PMID: 24948725 [PubMed - indexed for MEDLINE]
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3. N Engl J Med. 2014 Jun 19;370(25):2418-25. doi: 10.1056/NEJMra1312543.

Diagnostic clinical genome and exome sequencing.

Biesecker LG1, Green RC.

Author information:
1From the National Human Genome Research Institute, National Institutes of Health, Bethesda, MD (L.G.B.); and the Division of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, and Partners Healthcare Personalized Medicine - all in Boston (R.C.G.).

PMID: 24941179 [PubMed - indexed for MEDLINE]
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